Walther Straub Institute of Pharmacology and Toxicology
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PD Schredelseker, PhD

Johann Schredelseker, PD PhD

Cardiac Pharmacology

Contact

Ludwig-Maximilians-Universitaet Muenchen
Walther Straub Institute of Pharmacology and Toxicology
Nussbaumstrasse 26
80336 Muenchen
Germany

Phone: +49 89 2180-73831
Fax: +49 89 2180-73817

Research Group

Schredelseker Lab

Publications

1. Shimizu H*, Schredelseker J*, Huang J*, Lu K*, Naghdi S, Lu F., Franklin S, Fiji HDG, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnóczky G, Kwon O, and Chen JN (*equal contribution) (2015) Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. Elife, 4

2. Schredelseker J, Paz A, Lopez CJ, Altenbach C, Leung CS, Drexler MK, Chen JN, Hubbell WL, and Abramson J (2014) High-resolution structure and double electron electron resonance of the zebrafish Voltage Dependent Anion Channel 2 reveal an oligomeric population. J Biol Chem, 289: 12566-77

3. Van Handel B, Montel-Hagen A, Sasidharan R, Nakano H, Ferrari R, Boogerd CJ, Schredelseker J, Wang Y, Hunter S, Org T, Zhou J, Li X, Pellegrini M, Chen JN, Orkin SH, Kurdistani SK, Evans SM, Nakano A, and Mikkola HKA (2012). Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium. Cell, 150(3): 590-605

4. Pirone A, Schredelseker J, Tuluc P, Gravino E, Fortunato G, Flucher BE, Carsana A, Salvatore F, and Grabner M (2010). Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the CaV1.1α1 subunit. Am J Physiol-Cell Ph, 299(6): C1345-54

5. Dayal A*, Schredelseker J*, Franzini-Armstrong C, and Grabner M (*equal contribution) (2010). Skeletal muscle excitation-contraction coupling is independent of a conserved heptad repeat motif in the C-terminus of the DHPR β1a subunit. Cell Calcium, 47(6): 500-6

6. Schredelseker J, Dayal A, Shrivastav M and Grabner M (2010). Non-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling. Proc Natl Acad Sci U S A, 23;107(12): 5658-63

7. Schredelseker J*, Dayal A*, Schwerte T, Franzini-Armstrong C, and Grabner M (*equal contribution) (2009). Proper restoration of excitation-contraction coupling in the dihydropyridine receptor β1-null zebrafish relaxed is an exclusive function of the β1a subunit. J Biol Chem., 284(2): 1242-51

8. Flucher BE, Obermair G, Tuluc P, Schredelseker J, Kern G, and Grabner M (2005). The role of auxiliary dihydropyridine receptor subunits in muscle. J Muscle Res Cell Motil. 9: 1-6

9. Schredelseker J, DiBiase V, Obermair GJ, Felder ET, Flucher BE, Franzini-Armstrong C, and Grabner M (2005). The β1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle. Proc Natl Acad Sci U S A, 102(47): 17219-24

10. Schredelseker J and Pelster B (2004). The Isoform vatB1 of the vacuolar type ATPase subunit B is located in the apical membrane of skin cells in early larvae of zebrafish (Danio rerio). Developmental Dynamics, 230(3): 569-57